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Franco Lab Publications
**Franco lab members bolded 

2024

Ricarte-Filho JC, Reichenberger ER, Hinkle K, Isaza A, Bauer AJ, Franco AT.

TG-IGF1R: A Novel Receptor Tyrosine Kinase Fusion Oncogene in Pediatric Thyroid Cancer. Thyroid. Published online August 27, 2024.

doi:10.1089/thy.2024.0224

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Baran JA, Bojarsky M, Halada S, Ricarte-Filho JC, Isaza A, Franco AT, Surrey LF, Bhatti T, Baloch Z, Adzick NS, Mostoufi-Moab S, Kazahaya K, Bauer AJ.

Low-invasive somatic oncogenes and lymph node metastasis in pediatric papillary thyroid cancer: implications for prophylactic central neck dissection. Eur Thyroid J. 2024;13(4):e230265. Published 2024 Aug 2.

doi:10.1530/ETJ-23-0265

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Rossetti CL, Alves BL, Peçanha FLM, Franco AT, et al.

Defining the In Vivo Role of mTORC1 in Thyrocytes by Studying the TSC2 Conditional Knockout Mouse Model. Thyroid. 2024;34(8):1047-1057.

doi:10.1089/thy.2024.0053

2023

Ricarte-Filho JC, Casado-Medrano V, Reichenberger E, et al.

DICER1 RNase IIIb domain mutation trigger widespread miRNA dysregulation and MAPK activation in pediatric thyroid cancer. Front Endocrinol (Lausanne). 2023;14:1083382. Published 2023 Feb 21.

doi:10.3389/fendo.2023.1083382

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Branigan GP, Casado-Medrano V, O'Neill AB, et al.

Development of Novel Murine BRAFV600E Driven Papillary Thyroid Cancer Cell Lines for Modeling of Disease Progression and Preclinical Evaluation of Therapeutics. Cancers (Basel). 2023;15(3):879. Published 2023 Jan 31.

doi:10.3390/cancers15030879

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Campbell IM, Crowley TB, Jobaliya C, et al.

Platelet findings in 22q11.2 deletion syndrome correlate with disease manifestations but do not correlate with GPIb surface expression. Clin Genet. 2023;103(1):109-113.

doi:10.1111/cge.14227

2022

Goldfarb M, Franco AT.

Survivorship, Quality of Life, and Transition to Adult Care for Pediatric and Adolescent Thyroid Cancer Survivors. Thyroid. 2022;32(12):1471-1476.

doi:10.1089/thy.2022.0407

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Halada S, Baran JA, Bauer AJ, et al.

Clinicopathologic Characteristics of Pediatric Follicular Variant of Papillary Thyroid Carcinoma Subtypes: A Retrospective Cohort Study. Thyroid. 2022;32(11):1353 1361.

doi:10.1089/thy.2022.0239

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Halada S, Casado-Medrano V, Baran JA, et al.

Hormonal Crosstalk Between Thyroid and Breast Cancer. Endocrinology. 2022;163(7):bqac075.

doi:10.1210/endocr/bqac075

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Van Remortel BJ, Chehab L, Bauer AJ, et al.

Surgical outcomes in survivors of childhood cancer undergoing thyroidectomy: A single-institution experience. Pediatr Blood Cancer. 2022;69(6):e29674.

doi:10.1002/pbc.29674

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Casado-Medrano V, O'Neill A, Halada S, Laetsch TW, Bauer AJ, Franco AT.

NTRK-fusions in pediatric thyroid tumors: Current state and future perspectives. Cancer Genet. 2022;264-265:23-28. doi:10.1016/j.cancergen.2022.02.009

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Ricarte-Filho JC, Halada S, O'Neill A, et al.

The clinical aspect of NTRK-fusions in pediatric papillary thyroid cancer. Cancer Genet. 2022;262-263:57-63.

doi:10.1016/j.cancergen.2022.01.002

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Franco AT, Ricarte-Filho JC, Isaza A, et al.

Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers. J Clin Oncol. 2022;40(10):1081-1090.

doi:10.1200/JCO.21.01861

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Baran JA, Halada S, Bauer AJ, et al.

Indeterminate Thyroid Fine-Needle Aspirations in Pediatrics: Exploring Clinicopathologic Features and Utility of Molecular Profiling. Horm Res Paediatr. 2022;95(5):430-441. 

doi:10.1159/000526116

2021 
 

Caperton CO, Jolly LA, Massoll N, Bauer AJ, Franco AT.

Development of Novel Follicular Thyroid Cancer Models Which Progress to Poorly Differentiated and Anaplastic Thyroid Cancer. Cancers (Basel). 2021;13(5):1094. Published 2021 Mar 4. 

doi.org/10.3390/cancers13051094 

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Baran JA, Bauer AJ, Halada S, et al.

Clinical Course of Early Postoperative Hypothyroidism Following Thyroid Lobectomy in Pediatrics. Thyroid. 2021;31(12):1786-1793. 

doi:10.1089/thy.2021.0396

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Franco AT, Ricarte-Filho JC, Laetsch TW, Bauer AJ.

Oncogene-specific inhibition in the treatment of advanced pediatric thyroid cancer. J Clin Invest. 2021;131(18):e152696. doi:10.1172/JCI152696

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Jenjaroenpun P, Wongsurawat T, Wadley TD, et al.

Decoding the epitranscriptional landscape from native RNA sequences. Nucleic Acids Res. 2021;49(2):e7. 

doi:10.1093/nar/gkaa620

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Jia MR, Baran JA, Bauer AJ, et al.

Utility of Fine-Needle Aspirations to Diagnose Pediatric Thyroid Nodules. Horm Res Paediatr. 2021;94(7-8):263-274. doi:10.1159/000519307

2020
 

MacDonald L, Jenkins J, Purvis G, Lee J, Franco AT.

The Thyroid Tumor Microenvironment: Potential Targets for Therapeutic Intervention and Prognostication. Hormones & Cancer2020;11(5-6):205-         217. Published 2020 Jun 17. 

https://doi.org/10.1007/s12672-020-00390-6
 

Franco AT, Labourier E, Ablordeppey KK, et al.

miRNA expression can classify pediatric thyroid lesions and increases the diagnostic yield of mutation testing. Pediatric Blood & Cancer. 2020;67(6):e28276. Published 2020 Mar 20. 

https://doi.org/10.1002/pbc.28276

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Baran JA, Tsai SD, Isaza A, et al.

The Clinical Spectrum of PTEN Hamartoma Tumor Syndrome: Exploring the Value of Thyroid Surveillance. Horm Res Paediatr. 2020;93(11-12):634-642. 

doi:10.1159/000515731

2019
 

Jana A, Nookaew I, Singh J, Behkam B, Franco AT, Nain AS.

Crosshatch nanofiber networks of tunable interfiber spacing induce plasticity in cell migration and cytoskeletal response. FASEB Journal2019;33(10):10618-10632. Published 2019 June 24. 

https://doi.org/10.1096/fj.201900131R 

2017
 

Hinson AM, Massoll NA, Jolly LA, Stack BC Jr, Bodenner DL, Franco AT.

Structural alterations in tumor-draining lymph nodes before papillary thyroid carcinoma metastasis. Head & Neck. 2017;39(8):1639-1646. Published 2017 May 03. 

https://doi.org/10.1002/hed.24807

2016
 

Jolly LA, Massoll N, Franco AT.

Immune Suppression Mediated by Myeloid and Lymphoid Derived Immune Cells in the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by HrasG12V and Pten Loss. Journal of Clinical & Cellular Immunology. 2016;7(5):451. Published 2016 Sep 16. 

https://doi.org/10.4172/2155-9899.1000451 

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Jolly LA, Novitskiy S, Owens P, et al.

Fibroblast-Mediated Collagen Remodeling Within the Tumor. Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss. Cancer Research. 2016;76(7):1804-1813. Published 2016 April 1. 

https://doi.org/10.1158/0008- 5472.CAN-15-2351 

2015
 

Franco AT, Corken A, Ware J.

Platelets at the interface of thrombosis, inflammation, and cancer. Blood. 2015;126(5):582-588. Published 2015 Jul 30.

https://doi.org/10.1182/blood-2014-08-531582​ 

2011
 

Franco AT, Malaguarnera R, Refetoff S, et al.

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. PNAS. 2011;108(4):1615-1620. Published 2011 Jan 25. 

https://doi.org/10.1073/pnas.1015557108

2008
 

Franco AT, Johnston E, Krishna U, et al.

Regulation of gastric carcinogenesis by Helicobacter pylori virulence factors. Cancer Research. 2008;68(2):379-387. Published 2008 Jan 15. 

https://doi.org/10.1158/0008-5472.CAN-07-0824 

2005
 

Franco AT, Israel DA, Washington MK, et al.

Activation of beta-catenin by carcinogenic Helicobacter pylori. PNAS. 2005;102(30):10646-10651. Published 2005 Jul 26. 

https://doi.org/10.1073/pnas.0504927102

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francoa1@chop.edu

215-590-1066

Department of Diabetes & Endocrinology.

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© 2021 Franco Research Laboratory 2021 
Children's Hospital of Philadelphia

3615 Civic Center Blvd, PA 19104
(215) 590-3800
 

 

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